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What is Valtrex?
Valtrex (valacyclovir hydrochloride) is an oral antiviral used to manage herpes infections including cold sores, shingles, and genital herpes. It reduces symptoms and outbreak duration.
How It Works
After ingestion, Valtrex converts into acyclovir, which blocks viral DNA polymerase and replication. Best taken at the first sign of symptoms.
Dosage Information
- Cold Sores: 2g twice in one day.
- Genital Herpes: 500mg twice daily for 3–10 days.
Hydration is important during treatment.
Side Effects
May include headache, nausea, dizziness. Rare: confusion, hallucinations in renal-impaired patients.
Warnings & Interactions
Use with caution in renal disease. May interact with nephrotoxic drugs (NSAIDs, cyclosporine). Safe in pregnancy under medical guidance.
Frequently Asked Questions
Yes, daily suppressive therapy with Valtrex is often prescribed to reduce outbreak frequency and transmission risk.
It is generally considered safe under supervision of a healthcare provider.
No. It suppresses symptoms and reduces outbreaks, but does not eliminate the virus.
Discuss with your doctor — especially if you take kidney-affecting drugs like NSAIDs or cyclosporine.
Medical Disclaimer
This website provides informational overviews of medications and does not offer medical advice, diagnosis, or treatment. Always consult a licensed healthcare provider before starting or changing any medication.
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This page was last medically reviewed: June 2025
Dosage guidelines follow current CDC antiviral therapy recommendations.