Clomid (Clomiphene Citrate)

What is Clomid?

Clomid (clomiphene citrate) is a prescription medication used to stimulate ovulation in women who don’t ovulate regularly. It’s often the first-line treatment for infertility caused by PCOS, mild hormonal imbalances, or irregular menstrual cycles. Unlike hormone injections, Clomid works by prompting your own body to release the hormones needed for ovulation.

How It Works

Clomid blocks estrogen receptors in the hypothalamus — the part of your brain that regulates hormones. As a result, your body thinks estrogen levels are low and increases FSH and LH production, which triggers the ovaries to mature and release an egg. It’s most effective when taken early in the menstrual cycle, usually between days 3 and 5.

Dosage

• Standard Protocol: 50 mg once daily for 5 days, starting on Day 3–5 of your cycle.
• If no ovulation: Dose may increase to 100 mg in future cycles, under medical supervision.
• Maximum cycles: Typically limited to 3–6 rounds.

Stay hydrated and report any side effects to your doctor. Ovulation usually occurs 5–10 days after the last tablet.

Side Effects

Clomid is generally well-tolerated, but you might notice: hot flashes, mood swings, headaches, bloating or pelvic discomfort. Rarely, ovarian enlargement or vision changes can occur. If you experience severe pain or blurred vision, stop and call your provider.

Warnings & Precautions

Not for women with liver disease, ovarian cysts (non-PCOS), or unexplained abnormal bleeding. Not recommended for use beyond 6 cycles due to ovarian risk. Tell your doctor if you're taking antidepressants, thyroid meds, or other hormonal treatments. Not for use during pregnancy.